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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
30
Human Site:
S1306
Identified Species:
60
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
S1306
G
R
T
G
A
G
K
S
S
L
A
S
G
L
L
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
I1068
E
S
A
E
G
E
I
I
I
D
G
I
N
I
A
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
D1168
S
F
P
R
L
V
A
D
R
W
L
A
A
N
V
Dog
Lupus familis
XP_547113
1504
165780
S1307
G
R
T
G
A
G
K
S
S
L
A
G
G
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
S1301
G
R
T
G
A
G
K
S
S
L
A
W
G
L
L
Rat
Rattus norvegicus
O88269
1502
164977
S1305
G
R
T
G
A
G
K
S
S
L
T
W
G
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
S1340
G
R
T
G
A
G
K
S
S
L
T
L
G
L
F
Chicken
Gallus gallus
Q5F364
1525
170953
S1328
G
R
T
G
A
G
K
S
S
L
T
L
G
L
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
S1321
G
R
T
G
A
G
K
S
S
L
T
L
G
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
Q1111
G
L
H
D
L
R
R
Q
I
S
I
I
P
Q
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
S1338
G
R
T
G
S
G
K
S
T
L
I
Q
V
L
F
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
S1313
G
R
T
G
A
G
K
S
S
L
T
L
A
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
93.3
N.A.
93.3
86.6
N.A.
80
80
N.A.
80
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
13.3
93.3
N.A.
93.3
86.6
N.A.
80
80
N.A.
80
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
67
0
9
0
0
0
25
9
17
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
9
0
9
0
0
0
0
0
% D
% Glu:
9
0
0
9
0
9
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
42
% F
% Gly:
84
0
0
75
9
75
0
0
0
0
9
9
59
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
17
0
17
17
0
9
0
% I
% Lys:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
17
0
0
0
0
75
9
34
0
75
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
9
0
9
0
% Q
% Arg:
0
75
0
9
0
9
9
0
9
0
0
0
0
0
0
% R
% Ser:
9
9
0
0
9
0
0
75
67
9
0
9
0
0
0
% S
% Thr:
0
0
75
0
0
0
0
0
9
0
42
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
17
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _